Saw palmetto

Synonym(s): Saw Palmetto Extract, Serenoa repens
Nutrient group: plant extracts & active ingredients

Sources

Dietary sources 
The saw palm is a hermaphroditic fan palm and is found on sandy soils in the southeast of the USA. The plant owes its name to its toothed leaf stems. In phytotherapy the fruits are used, characterized primarily by their phytosterols and free fatty acid content, although there are significant differences in the composition depending on the quality of the extract.

Detailed information

Saw Palmetto in benign prostatic hyperplasia
Plant-based bioactive ingredients cannot reverse benign prostatic hyperplasia (BPH), but they can have a strengthening and invigorating effect on the weakened urinary organs and significantly improve symptoms (1). The phytosterols contained in saw palmetto such as beta-sitosterol, curcubitin and various bioflavonoids have a stabilizing effect on the prostate metabolism. The antiprostatic mechanism of action is not yet known, but it is certain that sitosterols have antiphlogistic and anti-edematous effects. Overall, the symptoms of incipient BHP can be improved by these plant extracts (2).

Saw palmetto extract (Serenoa repens) seems to have both antiphlogistic and hormone-modulating properties. It is assumed that the antiprostatic effect is due to a synergistic effect of several active ingredients. The Commission E names micturition complaints in BPH stages 1 and 2 as areas of application (1).

Indications

Effect Indication Dosage
Physiological effects
at a low intake

To improve micturition problems associated with benign prostatic hyperplasia (BPH):

Reduction of urge to urinate, improvement of urine flow, increase in urine volume, reduction of residual urine and decrease in urination at night

100 mg/d

Administration

General mode of administration
 
When
Saw palmetto extract should be taken between meals.
Side effects
No side effects are known to date.
Contraindications
No contraindications are known to date.

Interactions

Drug interactions (according to Gröber)
Prostate medication
(tamsulosin, finasteride)
A combined intake can support the effectiveness of the drugs.
Nutrient interactions
None No relevant interactions are known to date.

References

References

1) Monography BGA/BfArM (Commission E). 1989. monograph Sabal fructus (saw palmetto fruits). Federal Gazette. 43:G04BF.
2) Cabin, B. E. et al. 1990. Treatment of benign prostatic hyperplasia with phytosterols. Br J Urol. 66(6):639-41

References Interactions
Stargrove, M. B. et al. Herb, Nutrient and Drug Interactions: Clinical Implications and Therapeutic Strategies, 1
Edition. St. Louis, Missouri: Elsevier Health Sciences, 2008.
Gröber, U. Micronutrients: Metabolic Tuning –Prevention –Therapy, 3rd edition. Stuttgart: WVG Scientific Publishing Company Stuttgart, 2011.
Gröber, U. Arzneimittel und Mikronährstoffe: Medication-oriented supplementation, 3. updated and extended edition. Stuttgart: WVG Scientific Publishing Company Stuttgart, 2014.

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