Chronic fatigue syndrome

Micronutrient therapy

 Micronutrients for increased drive
L-phenylalanine can be synthesized in the body to phenylethylamine (PEA). PEA acts as a stimulatory neurotransmitter and increases attention and mental activity. It also enhances drive and improves mood. Laboratory diagnostic tests show that PEA blood levels are often greatly reduced in chronic fatigue syndrome (CFS) and depression, which is why patients can benefit from L-phenylalanine substitution.

Vitamin B6 is converted in the liver to pyridoxal 5-phosphate (P5P), which plays a central role as a cofactor in neurotransmitter synthesis and can lead to neurological disorders in the brain if the P5P level is inadequate. Diseases caused by a disorder of noradrenalin- and dopamine-dependent neurotransmission can be improved by a high dosage of P5P. Increased serotonin synthesis also positively influences non-specific symptoms such as insomnia, nervousness and anxiety. A typical sign of vitamin B6-deficiency is a lack of dream memory.

Reduced nicotinamide adenine dinucleotide (short NADH) can increase the production of the neurotransmitters dopamine and norepinephrine and modulate the uptake and release of the neurotransmitters into the synaptic cleft. Besides ATP, NADH seems to be a fundamental substance for multiple processes in the brain. As a central component in the antioxidative system of brain cells, NADH also plays an important role in slowing down aging processes. Patients with chronic fatigue and listlessness developed more zest for life and willingness to perform.

5-Hydroxytryptophan (5-HTP) is an intermediate stage in the endogenous conversion of the amino acid tryptophan into the neurotransmitter serotonin. In chronic fatigue syndrome, 5-HTP and serotonin appear to have a direct influence on the hypothalamic-pituitary adrenal axis and its stimulation. Serotonin levels are closely related to psychological changes such as depressive moods, anxiety and panic or aggression. It directly influences the sleep-wake rhythm, appetite control and pain perception. Substitution with 5-HTP increases the availability of serotonin in the synaptic cleft, thus increasing the drive effect. B vitamins Niacin, Vitamin B1 and Vitamin B6 are also essential for successful serotonin synthesis.

Diagnostic tests

Possible laboratory examination (Laboratory GANZIMMUN) Detailed information
adrenal stress index Cortisol in daily profile, DHEA Neurotransmitters and stress 
Nitrost Stress Profile Citrulline, Methylmalonic acid, Nitrophenylacetic acid Neurotransmitters and stress  
CSF-Panel 1 Catecholamines, DHEA, cortisol, serotonin, histamine Neurotransmitters and stress  
CSF panel 2 TSH, sTfR, vitamin B6, D, calcium, potassium, copper, magnesium, selenium, zinc, small blood count Neurotransmitters and stress  
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